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In patients with hypotension or severe coronary artery disease, Pentoxifylline should be used with caution, as a transient hypotensive effect is possible and, in isolated cases, might result in a reduction in coronary artery perfusion.
Particularly careful monitoring is required in patients with impaired renal function. In patients with a creatinine clearance of less than 30 mL/min, it may be necessary to reduce the daily dose of Pentoxifylline to one or two tablets to avoid accumulation. In patients with severely impaired liver function, the dosage may need to be reduced.
Effects on Ability to Drive and Use Machines: No effect known.
